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Breast Cancer Identifying Gene Variants Involved in Radiotherapy Toxicity Risk: A Q&A With Benjamin Smith, MD

Identifying Gene Variants Involved in Radiotherapy Toxicity Risk: A Q&A With Benjamin Smith, MD

Genomics could guide the decision about whether a patient should undergo implant reconstruction or autologous tissue-based reconstruction.

General Oncology FDA Guidance: Expansion Cohort Trials Expected to Modernize Oncology Trials

FDA Guidance: Expansion Cohort Trials Expected to Modernize Oncology Trials

There is a push to create innovative adaptive trial designs that include more patients and, subsequently, more generalizable data.

Breast Cancer Surgeon Attitudes May Influence Genetic Testing for Patients With Breast Cancer

Surgeon Attitudes May Influence Genetic Testing for Patients With Breast Cancer

The likelihood of a patient with breast cancer receiving genetic analysis more than doubled if she went to a surgeon with a high propensity for ordering such tests.

Lymphoma Liquid Biopsy May Predict Response to Therapy in Diffuse Large B-Cell Lymphoma

Liquid Biopsy May Predict Response to Therapy in Diffuse Large B-Cell Lymphoma

Circulating tumor DNA levels measured as early as 3 weeks post-therapy may provide clues about long-term outcomes in this lymphoma subtype.

Renal Cell Carcinoma Robotic Partial Nephrectomy Compared With Open, Laparoscopic Partial Nephrectomy

Robotic Partial Nephrectomy Compared With Open, Laparoscopic Partial Nephrectomy

A meta-analysis compared outcomes between the use of partial nephrectomy using a robotic surgical approach and open or laparoscopic partial nephrectomy.

Skin Cancer Exploring the Role of Immunotherapy in Melanoma Brain Metastases

Exploring the Role of Immunotherapy in Melanoma Brain Metastases

Although checkpoint inhibitors are active against melanoma-linked brain metastases, researchers are interested in exploring combination approaches.

Renal Cell Carcinoma Clues from DNA Repair Mechanisms Could Drive Novel Therapeutic Strategies

Clues from DNA Repair Mechanisms Could Drive Novel Therapeutic Strategies

Metabolites from the Krebs cycle were found to suppress the DNA-repair pathway required for the preservation of genomic integrity.

Lung Cancer Researchers Use Artificial Intelligence to Predict Patient Survival from Pathology Images in Lung Cancer

Researchers Use Artificial Intelligence to Predict Patient Survival from Pathology Images in Lung Cancer

Artificial intelligence techniques are being employed to build complex new multivariate prognostic models for patients with lung cancer and other malignancies.

Lymphoma Obinutuzumab in Follicular Lymphoma

Obinutuzumab in Follicular Lymphoma

Many patients with follicular lymphoma will be asymptomatic and present with variable cervical, axillary, and inguinal adenopathy.

Breast Cancer High BMI Linked With Lower Breast Cancer Risk in Premenopausal Women

High BMI Linked With Lower Breast Cancer Risk in Premenopausal Women

Having a high body mass index reduces the risk for developing breast cancer before menopause, but more research is needed to understand the biological mechanism.

General Oncology Bispecific Antibodies in Cancer

Bispecific Antibodies in Cancer

Interest in these bioengineered antibodies has been rekindled by the striking success seen in the treatment of some cancers with immunotherapies.

Multiple Myeloma Selinexor and Multiple Myeloma

Selinexor and Multiple Myeloma

Early preclinical and clinical data have shown that selinexor has broad activity against multiple hematologic malignancies and notable antimyeloma activity.

General Oncology Depression as a Side Effect: Exploring a Link Between Certain Cancer Treatments and Mental Health

Depression as a Side Effect: Exploring a Link Between Certain Cancer Treatments and Mental Health

Researchers are promoting physician and patient awareness about the potential tie between depression and certain therapies.

Skin Cancer Tapping Social Media for Skin Cancer Prevention: What You Can Do

Tapping Social Media for Skin Cancer Prevention: What You Can Do

Any images and personal stories that remind people about skin cancer, what to look for, even scars after surgery, really help save lives.

Lung Cancer Re-treatment With Checkpoint Inhibitors in Some Patients with NSCLC May Be Feasible

Re-treatment With Checkpoint Inhibitors in Some Patients with NSCLC May Be Feasible

Even after an adverse event due to treatment with a checkpoint inhibitor, some patients may benefit from re-treatment with drugs from this class.

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